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Cheesy Meatloaf Casserole

Cheesy Meatloaf Casserole

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Cheesy Meatloaf Casserole is a deliciously satisfying dish that combines savory ground beef with layers of rich cheddar cheese and crispy breadcrumbs, all baked to perfection. This comforting casserole is ideal for busy weeknight dinners or family gatherings, offering both heartiness and flavor in every bite. Its cheesy goodness makes it a favorite among both kids and adults, ensuring everyone leaves the table happy. With its make-ahead convenience, you can prepare this dish in advance and simply pop it in the oven when you’re ready to serve. Enjoy a delightful meal that brings everyone together!

  • Total Time: 1 hour 10 minutes
  • Yield: Serves approximately 8

Ingredients

Scale
  • 2 pounds ground beef
  • 1 cup breadcrumbs
  • 1 cup shredded cheddar cheese
  • 1/2 cup milk
  • 1/4 cup ketchup
  • 1/4 cup chopped onion
  • 2 eggs
  • to taste salt and pepper
  • 1 teaspoon garlic powder
  • 1 teaspoon Italian seasoning
  • 1 cup additional cheese for topping

Instructions

  1. Preheat your oven to 350°F (175°C) and grease a baking dish.
  2. In a large mixing bowl, combine ground beef, breadcrumbs, shredded cheddar, milk, ketchup, chopped onion, eggs, salt, pepper, garlic powder, and Italian seasoning. Mix until just combined.
  3. Transfer the mixture to the greased baking dish and shape into a loaf or spread evenly.
  4. Bake for 45 minutes until slightly pulling from edges and reaching an internal temperature of 155–160°F.
  5. Remove from the oven, sprinkle additional cheese on top, then return to bake for another 10–15 minutes until melted and bubbly.
  6. Let cool for a few minutes before slicing and serving with your favorite sides.
  • Author: Sarah
  • Prep Time: 15 minutes
  • Cook Time: 55 minutes
  • Category: Main
  • Method: Baking
  • Cuisine: American

Nutrition

  • Serving Size: 1 slice (about 180g)
  • Calories: 420
  • Sugar: 3g
  • Sodium: 640mg
  • Fat: 24g
  • Saturated Fat: 10g
  • Unsaturated Fat: 12g
  • Trans Fat: 0g
  • Carbohydrates: 18g
  • Fiber: 1g
  • Protein: 30g
  • Cholesterol: 120mg